| Reaction Details |
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 | Report a problem with these data |
| Target | Cation-dependent mannose-6-phosphate receptor |
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| Ligand | BDBM582013 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | General M6PR Binding Assay |
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| IC50 | 75±n/a nM |
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| Citation |  Bradley, BB; Thomas, EJ; K., PG; G., LJ; D., TE M6PR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES WIPOWO2023288015 Publication Date 1/19/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Cation-dependent mannose-6-phosphate receptor |
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| Name: | Cation-dependent mannose-6-phosphate receptor |
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| Synonyms: | M6PR | MPR46 | MPRD | MPRD_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30989.41 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_492874 |
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| Residue: | 277 |
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| Sequence: | MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSF
ESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIML
IYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS
PEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGC
DFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM
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| BDBM582013 |
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| n/a |
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| Name | BDBM582013 |
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| Synonyms: | WO2023288015, Compound Table12B.772 |
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| Type | Small organic molecule |
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| Emp. Form. | C111H172N24O46P4 |
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| Mol. Mass. | 2702.5816 |
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| SMILES | O[C@@H]1[C@@H](CCP(O)(O)=O)O[C@H](Oc2ccc(NC(=O)NCCCCc3cn(CCCCC(NC(=O)[C@@H](CCCCn4cc(CCCCNC(=O)Nc5ccc(O[C@H]6O[C@H](CCP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]6O)cc5)nn4)NC(=O)C(CCCn4cc(CCCCNC(=O)Nc5ccc(O[C@H]6O[C@H](CCP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]6O)cc5)nn4)N(=O)CCCn4cc(CCCCNC(=O)Nc5ccc(O[C@H]6O[C@H](CCP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]6O)cc5)nn4)C(=O)NCCOCCOCCOCCOCCC(O)=O)nn3)cc2)[C@@H](O)[C@H]1O |
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| Structure | 
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