| Reaction Details |
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 | Report a problem with these data |
| Target | Advanced glycosylation end product-specific receptor |
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| Ligand | BDBM582520 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Microscale Thermophoresis Assay |
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| Kd | 22.3±n/a nM |
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| Citation |  Banner, WK; Gaddam, B; Polisetti, DR; Andrews, RC; Victory, S Metabolites of [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4 yl}-phenoxy)-propyl]-diethyl-amine US Patent US11524942 Publication Date 12/13/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Advanced glycosylation end product-specific receptor |
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| Name: | Advanced glycosylation end product-specific receptor |
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| Synonyms: | AGER | RAGE | RAGE_HUMAN | Receptor for advanced glycosylation end products |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42800.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1339877 |
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| Residue: | 404 |
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| Sequence: | MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA
WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI
PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH
PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL
VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS
CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV
ILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP
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| BDBM582520 |
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| n/a |
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| Name | BDBM582520 |
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| Synonyms: | US11524942, Compound M2 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H36ClN3O2 |
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| Mol. Mass. | 518.089 |
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| SMILES | CCCCc1nc(cn1Cc1ccc(Oc2ccc(Cl)cc2)cc1)-c1ccc(OCCCNCC)cc1 |
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| Structure | 
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