| Reaction Details |
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 | Report a problem with these data |
| Target | Proteasome subunit alpha type-6 |
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| Ligand | BDBM588480 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Proteasome Inhibitory Activity |
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| IC50 | 8.20±n/a nM |
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| Citation |  Qin, Y Synthesis of peptide borate ester compound and use thereof US Patent US11542283 Publication Date 1/3/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteasome subunit alpha type-6 |
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| Name: | Proteasome subunit alpha type-6 |
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| Synonyms: | 27 kDa prosomal protein | Macropain iota chain | Multicatalytic endopeptidase complex iota chain | PROS-27 | PROS27 | PSA6_HUMAN | PSMA6 | Proteasome iota chain | p27K |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27399.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_106197 |
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| Residue: | 246 |
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| Sequence: | MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL
LDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIAD
ISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLE
KKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLV
ALAERD
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| BDBM588480 |
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| n/a |
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| Name | BDBM588480 |
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| Synonyms: | (S)-N-(2,5-dichlorobenzoyl)-3- methoxypropionamido-D-leucine borate citrate | US11542283, Compound V-8B |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27BCl2N2O10 |
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| Mol. Mass. | 561.174 |
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| SMILES | COC[C@H](NC(=O)c1cc(Cl)ccc1Cl)C(=O)N[C@@H](CC(C)C)B1OC(=O)CC(CC(O)=O)(O1)C(O)=O |r| |
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| Structure | 
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