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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Solute carrier family 22 member 2 | ||
| Ligand | BDBM589189 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | OCT2 Inhibition Assay | ||
| IC50 | 450±n/a nM | ||
| Citation |  Bacon, EM; Cai, ZR; Chen, X; Cottell, JJ; Desai, MC; Ji, M; Jin, H; Lazerwith, SE; Mish, MR; Morganelli, PA; Pyun, H; Taylor, JG; Trejo Martin, TA Substituted 1,4-methanopyrido[1′,2′:4,5]pyrazino[1,2-a]pyrimidines for treating viral infections US Patent US11548901 Publication Date 1/10/2023 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Solute carrier family 22 member 2 | |||
| Name: | Solute carrier family 22 member 2 | ||
| Synonyms: | OCT2 | Organic cation transporter 2 | S22A2_HUMAN | SLC22A2 | hOCT2 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 62591.01 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1484077 | ||
| Residue: | 555 | ||
| Sequence: |
| ||
| BDBM589189 | |||
| n/a | |||
| Name | BDBM589189 | ||
| Synonyms: | US11548901, Compound 100 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H21F2N3O4 | ||
| Mol. Mass. | 429.4166 | ||
| SMILES | Oc1c2C(=O)N3C4CCC(CC4)C3Cn2cc(C(=O)NCc2ccc(F)cc2F)c1=O |(7.73,-2.31,;7.73,-.77,;6.39,,;5.06,-.77,;5.06,-2.31,;3.73,,;2.39,-.77,;1.06,,;1.06,1.54,;2.39,2.31,;2.14,1.28,;2.14,.26,;3.73,1.54,;5.06,2.31,;6.39,1.54,;7.73,2.31,;9.06,1.54,;10.4,2.31,;11.73,1.54,;10.4,3.85,;11.73,4.62,;11.73,6.16,;10.4,6.93,;10.4,8.47,;11.73,9.24,;11.73,10.78,;13.06,8.47,;13.06,6.93,;14.4,6.16,;9.06,,;10.4,-.77,)| | ||
| Structure | 
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