| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
|---|
| Ligand | BDBM590790 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | CB1 and CB2 Receptor Binding Assay |
|---|
| IC50 | 0.600±n/a nM |
|---|
| Citation |  Elzein, E; Liu, J Cannabinoid receptor type 2 (CB2) modulators and uses thereof US Patent US11564928 Publication Date 1/31/2023 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 2 |
|---|
| Name: | Cannabinoid receptor 2 |
|---|
| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 39690.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P34972 |
|---|
| Residue: | 360 |
|---|
| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
|
|
|
|---|
| BDBM590790 |
|---|
| n/a |
|---|
| Name | BDBM590790 |
|---|
| Synonyms: | 6-(5-fluoropyridin-2-yl)-1-(2- morpholinoethyl)-2-oxo-N- (spiro[3.3]heptan-2-yl)-1,2- dihydro-1,8-naphthyridine-3-carboxamide | US11564928, Compound 37 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H30FN5O3 |
|---|
| Mol. Mass. | 491.5572 |
|---|
| SMILES | Fc1ccc(nc1)-c1cnc2n(CCN3CCOCC3)c(=O)c(cc2c1)C(=O)NC1CC2(CCC2)C1 |
|---|
| Structure | 
|
|---|
Search and Browse
