| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vasopressin V1a receptor |
|---|
| Ligand | BDBM593644 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Pharmacological Assay |
|---|
| Ki | 0.794±n/a nM |
|---|
| Citation |  Runtz-Schmitt, V; Schnider, P; Dolente, C; Fasching, B Spiro-oxazolones US Patent US11578077 Publication Date 2/14/2023 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Vasopressin V1a receptor |
|---|
| Name: | Vasopressin V1a receptor |
|---|
| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor |
|---|
| Type: | Receptor |
|---|
| Mol. Mass.: | 46820.18 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P37288 |
|---|
| Residue: | 418 |
|---|
| Sequence: | MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY
IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV
QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
|
|
|
|---|
| BDBM593644 |
|---|
| n/a |
|---|
| Name | BDBM593644 |
|---|
| Synonyms: | 2'-(7,7-dimethyl-1'H,7H- spiro[furo[3,4-b]pyridine-5,4'- piperidin]-1'-yl)-1,3-dihydro-4'H- spiro[indene-2,5'-[1,3]oxazol]-4'-one | US11578077, Example 39 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H25N3O3 |
|---|
| Mol. Mass. | 403.4736 |
|---|
| SMILES | CC1(C)OC2(CCN(CC2)C2=NC(=O)C3(Cc4ccccc4C3)O2)c2cccnc12 |t:11| |
|---|
| Structure | 
|
|---|
Search and Browse
