| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM593911 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Inhibition for Dopamine D3 Receptor |
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| Ki | 0.079±n/a nM |
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| Citation |  Tobinaga, H; Masuda, K Condensed ring compounds having dopamine D3 receptor antagonistic effect US Patent US11578084 Publication Date 2/14/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DRD3 | DRD3_HUMAN | Dopamine D3 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44213.40 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_105671 |
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| Residue: | 400 |
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| Sequence: | MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM593911 |
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| n/a |
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| Name | BDBM593911 |
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| Synonyms: | US11578084, Compound II-2 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H35F3N4O3S |
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| Mol. Mass. | 576.673 |
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| SMILES | CN1Cc2c(cccc2C(=O)NC23CCC(CCN4CCc5nc(OCC(F)(F)F)sc5CC4)(CC2)CC3)C1=O |
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| Structure | 
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