| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 3 |
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| Ligand | BDBM123082 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Scintillation Proximity Assay |
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| Ki | 2.30±n/a nM |
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| Citation |  Fetscher, A; Scher, JM Pharmaceutical formulations comprising CCR3 antagonists US Patent US11612596 Publication Date 3/28/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| C-C chemokine receptor type 3 |
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| Name: | C-C chemokine receptor type 3 |
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| Synonyms: | C-C CKR-3 | C-C chemokine receptor type 3 (CCR3) | CC-CKR-3 | CCR-3 | CCR3 | CCR3_HUMAN | CD_antigen=CD193 | CKR3 | CMKBR3 | Eosinophil eotaxin receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41053.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51677 |
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| Residue: | 355 |
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| Sequence: | MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILI
KYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSE
IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEE
TLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRL
IFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVI
YAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF
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| BDBM123082 |
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| n/a |
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| Name | BDBM123082 |
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| Synonyms: | US10213421, Example 8 | US11612596, Example 8. | US8742115, 22 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H38ClN5O3 |
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| Mol. Mass. | 540.097 |
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| SMILES | CC(C)N(C)C(=O)c1cc(C)nc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 |r| |
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| Structure | 
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