Reaction Details |
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Target | ATP-sensitive inward rectifier potassium channel 10 |
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Ligand | BDBM600745 |
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Substrate/Competitor | n/a |
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Meas. Tech. | thallium-flux assay |
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IC50 | >30000±n/a nM |
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Citation | Swale, DR; Foil, LD Method for controlling hematophagous or sap-feeding arthropods US Patent US11632953 Publication Date 4/25/2023 |
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More Info.: | Get all data from this article, Assay Method |
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ATP-sensitive inward rectifier potassium channel 10 |
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Name: | ATP-sensitive inward rectifier potassium channel 10 |
Synonyms: | ATP-dependent inwardly rectifying potassium channel Kir4.1 | Inward rectifier K(+) channel Kir1.2 | KCJ10_HUMAN | KCNJ10 | Potassium channel, inwardly rectifying subfamily J member 10 |
Type: | PROTEIN |
Mol. Mass.: | 42513.64 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_105175 |
Residue: | 379 |
Sequence: | MTSVAKVYYSQTTQTESRPLMGPGIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFI
DMQWRYKLLLFSATFAGTWFLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFL
FSLESQTTIGYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIR
FSQHAVVASHNGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQV
DTASDSPFLILPLTFYHVVDETSPLKDLPLRSGEGDFELVLILSGTVESTSATCQVRTSY
LPEEILWGYEFTPAISLSASGKYIADFSLFDQVVKVASPSGLRDSTVRYGDPEKLKLEES
LREQAEKEGSALSVRISNV
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BDBM600745 |
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n/a |
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Name | BDBM600745 |
Synonyms: | US11632953, Compound 1 | US11632953, Compound VU041 |
Type | Small organic molecule |
Emp. Form. | C19H20F3N3O |
Mol. Mass. | 363.3768 |
SMILES | FC(F)(F)c1nn(CC(=O)N2CCCc3ccccc23)c2CCCCc12 |
Structure |
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