| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Inward rectifier potassium channel 2 |
|---|
| Ligand | BDBM600751 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | thallium-flux assay |
|---|
| IC50 | >30000±n/a nM |
|---|
| Citation |  Swale, DR; Foil, LD Method for controlling hematophagous or sap-feeding arthropods US Patent US11632953 Publication Date 4/25/2023 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Inward rectifier potassium channel 2 |
|---|
| Name: | Inward rectifier potassium channel 2 |
|---|
| Synonyms: | Cardiac inward rectifier potassium channel | IRK-1 | IRK1 | Inward rectifier K(+) channel Kir2.1 | KCNJ2 | KCNJ2_HUMAN | Potassium channel, inwardly rectifying subfamily J member 2 | hIRK1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 48281.20 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1515520 |
|---|
| Residue: | 427 |
|---|
| Sequence: | MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFIN
VGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGK
ACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVM
AKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEG
EYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEG
MVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARD
LAEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTDTPPDIDLHNQASVPLEPRP
LRRESEI
|
|
|
|---|
| BDBM600751 |
|---|
| n/a |
|---|
| Name | BDBM600751 |
|---|
| Synonyms: | US11632953, Compound 9 | VU0652954 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H26F3N3O |
|---|
| Mol. Mass. | 369.4244 |
|---|
| SMILES | FC(F)(F)c1nn(CC(=O)N2CCCC3CCCCC23)c2CCCCc12 |
|---|
| Structure | 
|
|---|
Search and Browse
