| Reaction Details |
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 | Report a problem with these data |
| Target | cAMP-specific 3',5'-cyclic phosphodiesterase 7B |
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| Ligand | BDBM607116 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Assay |
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| IC50 | <10.00±n/a nM |
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| Citation |  Santora, VJ; Chen, M; Chung, D Substituted benzoxazole and benzofuran compounds as PDE7 inhibitors US Patent US11685745 Publication Date 6/27/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| cAMP-specific 3',5'-cyclic phosphodiesterase 7B |
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| Name: | cAMP-specific 3',5'-cyclic phosphodiesterase 7B |
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| Synonyms: | 3',5'-cyclic phosphodiesterase | PDE7B | PDE7B_HUMAN | Phosphodiesterase 7B | Phosphodiesterase 7B (PDE7B) | cAMP-specific 3',5'-cyclic phosphodiesterase 7B |
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| Type: | Enzyme |
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| Mol. Mass.: | 51842.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9NP56 |
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| Residue: | 450 |
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| Sequence: | MSCLMVERCGEILFENPDQNAKCVCMLGDIRLRGQTGVRAERRGSYPFIDFRLLNSTTYS
GEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGMWDFDIF
LFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAAD
VTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMS
VLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHN
KDLRLEDAQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEIS
PLCNQQKDSIPSIQIGFMSYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLLPRQ
HRSRGSSGSGPDHDHAGQGTESEEQEGDSP
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| BDBM607116 |
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| n/a |
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| Name | BDBM607116 |
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| Synonyms: | US11685745, Example 336 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22ClF2N3O3 |
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| Mol. Mass. | 449.878 |
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| SMILES | FC1(F)[C@H]2CC(C[C@@H]12)NC(=O)c1cc2cc(Cl)c3NC(=O)NC4(CCCCC4)c3c2o1 |r,$;;;;;;;;;;;;;;;;;;;;O;;;;;;;;;;$| |
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| Structure | 
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