| Reaction Details |
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 | Report a problem with these data |
| Target | Programmed cell death 1 ligand 1 |
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| Ligand | BDBM482417 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme-Linked Immunosorbent Assay ELISA |
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| IC50 | <5±n/a nM |
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| Citation |  Lange, C; Malathong, V; Mali, VR; McMahon, J; McMurtrie, DJ; Punna, S; Roth, HS; Singh, R; Wang, Y; Yang, J; Zhang, P Immunomodulator compounds US Patent US11708326 Publication Date 7/25/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Programmed cell death 1 ligand 1 |
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| Name: | Programmed cell death 1 ligand 1 |
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| Synonyms: | B7 homolog 1 | B7-H1 | B7H1 | B7H1 | CD274 | CD_antigen=CD274 | PD-L1 | PD1L1_HUMAN | PDCD1 ligand 1 | PDCD1L1 | PDCD1LG1 | PDL1 | Programmed cell death 1 ligand 1 | Programmed death ligand 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33278.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109807 |
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| Residue: | 290 |
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| Sequence: | MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEME
DKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGG
ADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTT
TTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTH
LVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEET
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| BDBM482417 |
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| n/a |
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| Name | BDBM482417 |
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| Synonyms: | US10919852, Compound TABLE 1.116 | US11708326, Compound TABLE 1.116 |
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| Type | Small organic molecule |
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| Emp. Form. | C38H40Cl2N4O6 |
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| Mol. Mass. | 719.653 |
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| SMILES | CN(C)CCCOc1cccc(c1Cl)-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN[C@@](C)(CO)C(O)=O)cc1Cl |r| |
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| Structure | 
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