| Reaction Details |
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 | Report a problem with these data |
| Target | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial |
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| Ligand | BDBM613046 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Apoptosis Inhibition Assay |
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| EC50 | 5.50±n/a nM |
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| Citation |  Zhang, Z; Wang, X; Huang, S; Jiang, X; Li, L; Zhang, Z; Han, J Apoptosis inhibitors US Patent US11725000 Publication Date 8/15/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial |
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| Name: | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial |
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| Synonyms: | 1.3.5.1 | Iron-sulfur subunit of complex II | SDH | SDH1 | SDHB | SDHB_HUMAN | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial |
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| Type: | PROTEIN |
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| Mol. Mass.: | 31643.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_117429 |
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| Residue: | 280 |
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| Sequence: | MAAVVALSLRRRLPATTLGGACLQASRGAQTAAATAPRIKKFAIYRWDPDKAGDKPHMQT
YEVDLNKCGPMVLDALIKIKNEVDSTLTFRRSCREGICGSCAMNINGGNTLACTRRIDTN
LNKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDESQEGKQQYLQSIEEREKL
DGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSL
YRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKEKKASV
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| BDBM613046 |
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| n/a |
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| Name | BDBM613046 |
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| Synonyms: | US11725000, Compound 309 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H34F3N3O4S |
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| Mol. Mass. | 625.701 |
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| SMILES | Cc1cc(nc(n1)S(=O)(=O)CCC(OCc1ccc(F)cc1F)c1ccccc1)-c1cc(F)c(=O)n(CC2CCCCC2)c1 |
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| Structure | 
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