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TargetB-cell lymphoma 6 protein
LigandBDBM618580
Substrate/Competitorn/a
Meas. Tech.HTRF Assay
IC50 6.31±n/a nM
Citation Bellenie, BRCheung, KMDavis, OAHoelder, SHuckvale, RCollie, GMeniconi, MBrennan, ALloyd, MG BCL6 INHIBITORS US Patent US20230287003 Publication Date 9/14/2023
More Info.:Get all data from this article,  Assay Method
 
B-cell lymphoma 6 protein
Name:B-cell lymphoma 6 protein
Synonyms:B-cell lymphoma 5 protein | B-cell lymphoma 6 protein | BCL-5 | BCL-6 | BCL5 | BCL6 | BCL6_HUMAN | BCoR-BCL6 | LAZ3 | Protein LAZ-3 | ZBTB27 | ZNF51 | Zinc finger and BTB domain-containing protein 27 | Zinc finger protein 51
Type:PROTEIN
Mol. Mass.:78866.89
Organism:Homo sapiens
Description:ChEMBL_117695
Residue:706
Sequence:
MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSI
FTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDT
CRKFIKASEAEMVSAIKPPREEFLNSRMLMPQDIMAYRGREVVENNLPLRSAPGCESRAF
APSLYSGLSTPPASYSMYSHLPVSSLLFSDEEFRDVRMPVANPFPKERALPCDSARPVPG
EYSRPTLEVSPNVCHSNIYSPKETIPEEARSDMHYSVAEGLKPAAPSARNAPYFPCDKAS
KEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPTESCSSKNACILQASG
SPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGPEQAELGRLSPRAYTAPPACQPPMEP
ENLDLQSPTKLSASGEDSTIPQASRLNNIVNRSMTGSPRSSSESHSPLYMHPPKCTSCGS
QSPQHAEMCLHTAGPTFPEEMGETQSEYSDSSCENGAFFCNECDCRFSEEASLKRHTLQT
HSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEK
PYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHC
EKCNLHFRHKSQLRLHLRQKHGAITNTKVQYRVSATDLPPELPKAC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM618580
n/a
NameBDBM618580
Synonyms:US20230287003, Example 12x
TypeSmall organic molecule
Emp. Form.C25H25ClF4N6O3
Mol. Mass.568.951
SMILESCn1c2ccc(Nc3nc(ncc3Cl)N3CC(F)(F)C[C@@H]3CO)cc2c2N[C@@H](C3CC3)C(F)(F)COc2c1=O |r|
Structure
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