| Reaction Details |
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 | Report a problem with these data |
| Target | Galectin-1 |
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| Ligand | BDBM620281 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Evaluation of Compound Inhibitory Activity (IC50) |
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| IC50 | 520±n/a nM |
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| Citation |  BOLLLI, M; GATFIELD, J; GRISOSTOMI, C; REMEN, L; SAGER, C; ZUMBRUNN, C SPIRO DERIVATIVES OF ALPHA-D-GALACTOPYRANOSIDES US Patent US20230295182 Publication Date 9/21/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Galectin-1 |
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| Name: | Galectin-1 |
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| Synonyms: | 14 kDa lectin | Galaptin | HPL | LEG1_HUMAN | LGALS1 | Lactose-binding lectin 1 | Lectin galactoside-binding soluble 1 | Putative MAPK-activating protein PM12 |
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| Type: | beta galactoside-binding protein |
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| Mol. Mass.: | 14713.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09382 |
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| Residue: | 135 |
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| Sequence: | MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIV
CNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINY
MAADGDFKIKCVAFD
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| BDBM620281 |
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| n/a |
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| Name | BDBM620281 |
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| Synonyms: | (2R,3R,4S,5R,6R)-6-((1-oxa-2-azaspiro[4.5]dec-2-en-3-yl)methyl)-2- (hydroxymethyl)-5-methoxy-4-(4-(2,3,4-trifluorophenyl)-1H-1,2,3-triazol-1- yl)tetrahydro-2H-pyran-3-ol | US20230295182, Example 1.13 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H29F3N4O5 |
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| Mol. Mass. | 510.5061 |
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| SMILES | CO[C@H]1[C@@H](CC2=NOC3(C2)CCCCC3)O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(F)c(F)c1F |t:5| |
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| Structure | 
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