| Reaction Details |
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 | Report a problem with these data |
| Target | N-formyl peptide receptor 2 |
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| Ligand | BDBM620556 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | cAMP Assay |
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| EC50 | 0.100±n/a nM |
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| Citation |  Shirude, PS; Rachamreddy, CR; Baligar, V; Seshadri, B; Madduri, SR; Kick, EK; Wurtz, NR OXOPYRROLIDINE UREA FPR2 AGONISTS US Patent US20230303513 Publication Date 9/28/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| N-formyl peptide receptor 2 |
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| Name: | N-formyl peptide receptor 2 |
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| Synonyms: | ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 38968.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25090 |
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| Residue: | 351 |
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| Sequence: | METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVT
TICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIA
LDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNF
ASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPL
RVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPM
LYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
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| BDBM620556 |
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| n/a |
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| Name | BDBM620556 |
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| Synonyms: | US20230303513, Example 4 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H24F2N4O5 |
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| Mol. Mass. | 498.4787 |
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| SMILES | COc1cc(F)c([C@@H]2CN(C(=O)[C@H]2NC(=O)Nc2ccccc2)c2c(OC)ccn(C)c2=O)c(F)c1 |r| |
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| Structure | 
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