| Reaction Details |
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 | Report a problem with these data |
| Target | fMet-Leu-Phe receptor |
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| Ligand | BDBM620576 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | cAMP Assay |
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| EC50 | 0.600±n/a nM |
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| Citation |  Shirude, PS; Rachamreddy, CR; Baligar, V; Seshadri, B; Madduri, SR; Kick, EK; Wurtz, NR OXOPYRROLIDINE UREA FPR2 AGONISTS US Patent US20230303513 Publication Date 9/28/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| fMet-Leu-Phe receptor |
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| Name: | fMet-Leu-Phe receptor |
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| Synonyms: | FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38456.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_4503779 |
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| Residue: | 350 |
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| Sequence: | METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
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| BDBM620576 |
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| n/a |
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| Name | BDBM620576 |
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| Synonyms: | US20230303513, Example 17 | US20230303513, Example 20 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H31ClF2N4O5 |
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| Mol. Mass. | 601.041 |
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| SMILES | COCCn1cccc(N2C[C@H]([C@H](NC(=O)NC3CCc4cc(Cl)ccc4C3)C2=O)c2c(F)cc(OC)cc2F)c1=O |r| |
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| Structure | 
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