| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2B adrenergic receptor |
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| Ligand | BDBM626180 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SPR Assay |
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| IC50 | 1460±n/a nM |
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| Citation |  Bell, AS; Schreyer, AM; Versluys, S Pyrazolopyrimidine compounds as adenosine receptor antagonists US Patent US11786528 Publication Date 10/17/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-2B adrenergic receptor |
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| Name: | Alpha-2B adrenergic receptor |
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| Synonyms: | ADA2B_HUMAN | ADRA2B | ADRA2L1 | ADRA2RL1 | Adrenergic alpha2B | Adrenergic receptor | Adrenergic receptor alpha | Adrenergic, alpha-2B-, receptor [Homo sapiens] | Alpha-2 adrenergic receptor subtype C2 | Alpha-2B adrenoceptor | Alpha-2B adrenoreceptor | Alpha-2BAR |
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| Type: | Enzyme |
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| Mol. Mass.: | 49964.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P18089 |
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| Residue: | 450 |
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| Sequence: | MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
EEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRR
AQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSS
LNPVIYTIFNQDFRRAFRRILCRPWTQTAW
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| BDBM626180 |
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| n/a |
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| Name | BDBM626180 |
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| Synonyms: | US11786528, Example 40 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14N6O2 |
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| Mol. Mass. | 322.3214 |
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| SMILES | COc1ccccc1Cn1cc2c(N)nc(nc2n1)-c1cnco1 |
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| Structure | 
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