| Reaction Details |
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 | Report a problem with these data |
| Target | Transcriptional enhancer factor TEF-4 |
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| Ligand | BDBM626336 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HTRF Assay |
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| IC50 | 70.0±n/a nM |
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| Citation |  Zbieg, JR; Beroza, PP Therapeutic compounds and methods of use US Patent US11787775 Publication Date 10/17/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Transcriptional enhancer factor TEF-4 |
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| Name: | Transcriptional enhancer factor TEF-4 |
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| Synonyms: | TEA domain family member 2 | TEAD-2 | TEAD2 | TEAD2_HUMAN | TEF4 | Transcriptional enhancer factor TEF-4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49241.42 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_119051 |
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| Residue: | 447 |
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| Sequence: | MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIY
PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLK
DQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPF
SQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPP
DAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLV
KFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVET
ERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQEL
LLCTAYVFEVSTSERGAQHHIYRLVRD
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|
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| BDBM626336 |
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| n/a |
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| Name | BDBM626336 |
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| Synonyms: | 2-[[[4-fluoro-7-(4-isopropylphenyl)- 2,3-dihydrobenzofuran-5- yl]amino]methyl]prop-2-enoic acid | US11787775, Compound 21 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22FNO3 |
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| Mol. Mass. | 355.4027 |
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| SMILES | CC(C)c1ccc(cc1)-c1cc(NCC(=C)C(O)=O)c(F)c2CCOc12 |
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| Structure | 
|
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