| Reaction Details |
|---|
 | Report a problem with these data |
| Target | fMet-Leu-Phe receptor |
|---|
| Ligand | BDBM632307 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays |
|---|
| EC50 | 0.200±n/a nM |
|---|
| Citation |  Shirude, PS; Rachamreddy, CR; Chattopadhyay, AK; Seshadri, B; Baligar, V; Madduri, SR; Kick, EK; Wurtz, NR OXOPYRROLIDINE FPR2 AGONISTS US Patent US20230348426 Publication Date 11/2/2023 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| fMet-Leu-Phe receptor |
|---|
| Name: | fMet-Leu-Phe receptor |
|---|
| Synonyms: | FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 38456.14 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_4503779 |
|---|
| Residue: | 350 |
|---|
| Sequence: | METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
|
|
|
|---|
| BDBM632307 |
|---|
| n/a |
|---|
| Name | BDBM632307 |
|---|
| Synonyms: | US20230348426, Example 577 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H29F2N3O5 |
|---|
| Mol. Mass. | 537.5545 |
|---|
| SMILES | COc1ccc(cc1)[C@@H]1CN(C(=O)[C@H]1NC(=O)c1ccc(OC(F)F)cc1)c1c(C)ccn(C2CCC2)c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
