| Reaction Details |
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 | Report a problem with these data |
| Target | Myelin transcription factor 1 |
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| Ligand | BDBM633056 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Assay |
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| IC50 | 4.00±n/a nM |
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| Citation |  SZYCHOWSKI, J; LIU, B; DIETRICH, E; PERRYMAN, A; CRANE, SN; TRUONG, VL; ABDOLI, A; BOUCHARD, A QUINAZOLINONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME US Patent US20230348456 Publication Date 11/2/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Myelin transcription factor 1 |
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| Name: | Myelin transcription factor 1 |
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| Synonyms: | KIAA0835 | KIAA1050 | MTF1 | MYT1 | MYT1_HUMAN | MYTI | Myelin transcription factor I | PLPB1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 122258.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_942118 |
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| Residue: | 1121 |
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| Sequence: | MSLENEDKRARTRSKALRGPPETTAADLSCPTPGCTGSGHVRGKYSRHRSLQSCPLAKKR
KLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDASVSDESEGTLEGAEAETS
GQDEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLV
EEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSL
EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE
EEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRK
STVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLGLGEPGKAAKPL
DTVRKSYYSKDPSRAEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMH
ENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQPQTGDPSKSSSNSD
RILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFDAQVFGKRML
APKIQTSETSPKAFQCFDYSQDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKSVD
IEVDENGTLDLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSS
QASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVT
LTNFKLKFLSKDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSA
DLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVG
LGHISGKYASHRSASGCPLAARRQKEGSLNGSSFSWKSLKNEGPTCPTPGCDGSGHANGS
FLTHRSLSGCPRATFAGKKGKLSGDEVLSPKFKTSDVLENDEEIKQLNQEIRDLNESNSE
MEAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHME
PICEQNFDAYVSTLTDMYSNQDPENKDLLESIKQAVRGIQV
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| BDBM633056 |
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| n/a |
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| Name | BDBM633056 |
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| Synonyms: | US20230348456, Compound 77 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H16N8O |
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| Mol. Mass. | 420.4261 |
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| SMILES | Nc1c(cc(-n2cccn2)c2nc([nH]c(=O)c12)-c1ccncc1)-c1cccc2[nH]ncc12 |
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| Structure | 
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