| Reaction Details |
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 | Report a problem with these data |
| Target | Histone acetyltransferase KAT2B [719-832] |
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| Ligand | BDBM311444 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | PCAF AlphaLisa Binding Assay |
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| IC50 | 69.0±n/a nM |
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| Citation |  Albrecht, BK; Cote, A; Crawford, T; Duplessis, M; Good, AC; LeBlanc, Y; Magnuson, S; Nasveschuk, CG; Pastor, R; Romero, AF; Taylor, AM Therapeutic compounds and uses thereof US Patent US10155764 Publication Date 12/18/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone acetyltransferase KAT2B [719-832] |
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| Name: | Histone acetyltransferase KAT2B [719-832] |
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| Synonyms: | KAT2B | KAT2B_HUMAN | PCAF | PCAF (aa 719-832) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 13623.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92831[719-832] |
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| Residue: | 114 |
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| Sequence: | SKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLK
NRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK
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| BDBM311444 |
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| n/a |
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| Name | BDBM311444 |
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| Synonyms: | CHEM-US-00141 | US10155764, Example 32 | US10155764, Example 32A | US10155764, Example 32B |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25ClN6O |
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| Mol. Mass. | 412.916 |
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| SMILES | CN(C)C1CN(CCC1Nc1nn(C)c(=O)c2cccnc12)c1ccc(Cl)cc1 |
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| Structure | 
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