Reaction Details |
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Target | Histone acetyltransferase KAT2B [719-832] |
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Ligand | BDBM311502 |
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Substrate/Competitor | n/a |
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Meas. Tech. | PCAF AlphaLisa Binding Assay |
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IC50 | 36.0±n/a nM |
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Citation | Albrecht, BK; Cote, A; Crawford, T; Duplessis, M; Good, AC; LeBlanc, Y; Magnuson, S; Nasveschuk, CG; Pastor, R; Romero, AF; Taylor, AM Therapeutic compounds and uses thereof US Patent US10155764 Publication Date 12/18/2018 |
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More Info.: | Get all data from this article, Assay Method |
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Histone acetyltransferase KAT2B [719-832] |
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Name: | Histone acetyltransferase KAT2B [719-832] |
Synonyms: | KAT2B | KAT2B_HUMAN | PCAF | PCAF (aa 719-832) |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 13623.13 |
Organism: | Homo sapiens (Human) |
Description: | Q92831[719-832] |
Residue: | 114 |
Sequence: | SKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLK
NRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK
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BDBM311502 |
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n/a |
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Name | BDBM311502 |
Synonyms: | US10155764, Example 77 |
Type | Small organic molecule |
Emp. Form. | C27H30N4O2 |
Mol. Mass. | 442.5527 |
SMILES | C[C@H](Nc1nn(C)c(=O)c2ccccc12)[C@@H](N(C)C)c1ccc(OCc2ccccc2)cc1 |r| |
Structure |
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