| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 4 [368-440] |
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| Ligand | BDBM640357 |
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| Substrate/Competitor | n/a |
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| Ki | <100.0±n/a nM |
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| Citation |  Thatcher, GR; Xiong, R; Zhao, J; Li, Y Pyridinone-based epigenetic modifiers and uses thereof US Patent US11840533 Publication Date 12/12/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 4 [368-440] |
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| Name: | Bromodomain-containing protein 4 [368-440] |
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| Synonyms: | BRD4 | BRD4_HUMAN | Bromo domain 2 | Bromodomain-containing protein 4 (BD2) | Bromodomain-containing protein 4 (BRD4) Bromo 2 | Bromodomain-containing protein 4 (BRD4)(BD2) | Bromodomain-containing protein 4 (BRD4)(Bromo 2) | Bromodomain-containing protein 4 Bromo 2 domain(BRD4 BD2) | Bromodomain-containing protein 4 Bromodomain 2 (BRD4-2) | Bromodomain-containing protein 4 Domain 2 | HUNK1 |
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| Type: | Protein |
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| Mol. Mass.: | 8564.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | BD2 (368-440 aa) of O60885 |
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| Residue: | 73 |
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| Sequence: | KHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFS
NCYKYNPPDHEVV
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| BDBM640357 |
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| n/a |
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| Name | BDBM640357 |
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| Synonyms: | N-(1-(4-fluorobenzyl)-6-(7- hydroxy-1-methyl-1H- pyrrolo[2,3-c]pyridin-3-yl)- 1H-indazol-4- yl)methanesulfonamide | US11840533, Compound 30 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H20FN5O3S |
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| Mol. Mass. | 465.5 |
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| SMILES | Cn1cc(-c2cc(NS(C)(=O)=O)c3cnn(Cc4ccc(F)cc4)c3c2)c2ccnc(O)c12 |
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| Structure | 
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