| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM642627 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Adenosine Receptor Binding Assay |
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| Ki | 3.49±n/a nM |
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| Citation |  COHEN, CJ; KLUGE, AF; RAY, SS; HUTCHINSON, JH ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE US Patent US20230416245 Publication Date 12/28/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM642627 |
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| n/a |
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| Name | BDBM642627 |
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| Synonyms: | US20230416245, Compound 65 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24ClN5O3 |
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| Mol. Mass. | 405.879 |
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| SMILES | CNC(=O)[C@]12C[C@@H]1[C@H]([C@H](O)[C@@H]2O)n1cnc2c(NCC3CCC3)cc(Cl)nc12 |r| |
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| Structure | 
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