| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear receptor subfamily 1 group D member 1 |
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| Ligand | BDBM643183 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FRET Assay for REV-ERB Ligands |
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| IC50 | <1000±n/a nM |
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| Citation |  Walker, JK; Burris, TP; Sitaula, S; Chatterjee, A; D''Cunha, NC; Jacobsen, EJ; Blinn, JR REV-ERB AGONISTS US Patent US20240002380 Publication Date 1/4/2024 |
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| More Info.: | Get all data from this article, Assay Method |
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| Nuclear receptor subfamily 1 group D member 1 |
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| Name: | Nuclear receptor subfamily 1 group D member 1 |
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| Synonyms: | EAR-1 | EAR1 | HREV | NR1D1 | NR1D1_HUMAN | Rev-erbA-alpha | THRAL | V-erbA-related protein 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66822.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_958222 |
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| Residue: | 614 |
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| Sequence: | MTTLDSNNNTGGVITYIGSSGSSPSRTSPESLYSDNSNGSFQSLTQGCPTYFPPSPTGSL
TQDPARSFGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKSTS
NITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRI
NRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETS
PTQHPTPGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIF
TYAHDKLGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNGLRQ
APSSYPPTWPPGPAHHSCHQSNSNGHRLCPTHVYAAPEGKAPANSPRQGNSKNVLLACPM
NMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVL
MVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLF
TAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNN
MHSEKLLSFRVDAQ
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| BDBM643183 |
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| n/a |
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| Name | BDBM643183 |
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| Synonyms: | US20240002380, Example 14 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H14FN3O |
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| Mol. Mass. | 319.3324 |
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| SMILES | Cn1ncc2ccc(Oc3ccccc3-c3cccc(F)c3)nc12 |
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| Structure | 
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