| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear receptor subfamily 1 group D member 2 |
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| Ligand | BDBM643188 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FRET Assay for REV-ERB Ligands |
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| IC50 | >10000±n/a nM |
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| Citation |  Walker, JK; Burris, TP; Sitaula, S; Chatterjee, A; D''Cunha, NC; Jacobsen, EJ; Blinn, JR REV-ERB AGONISTS US Patent US20240002380 Publication Date 1/4/2024 |
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| More Info.: | Get all data from this article, Assay Method |
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| Nuclear receptor subfamily 1 group D member 2 |
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| Name: | Nuclear receptor subfamily 1 group D member 2 |
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| Synonyms: | EAR-1R | NR1D2 | NR1D2_HUMAN | Orphan nuclear hormone receptor BD73 | Rev-erb-beta | V-erbA-related protein 1-related |
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| Type: | PROTEIN |
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| Mol. Mass.: | 64639.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502200 |
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| Residue: | 579 |
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| Sequence: | MEVNAGGVIAYISSSSSASSPASCHSEGSENSFQSSSSSVPSSPNSSNSDTNGNPKNGDL
ANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKFSGMVLLCKVCGDVASGFHYGVHAC
EGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIP
KREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQEQLRPKPQLEQENIKS
SSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDH
CGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPI
DGFSQNENKNSYLCNTGGRMHLVCPLSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFA
KRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAG
DLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLI
MKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP
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| BDBM643188 |
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| n/a |
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| Name | BDBM643188 |
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| Synonyms: | US20240002380, Example 34 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H14F3NO |
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| Mol. Mass. | 365.3479 |
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| SMILES | FC(F)(F)c1cc(Oc2ccccc2-c2ccccc2)nc2ccccc12 |
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| Structure | 
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