| Reaction Details |
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 | Report a problem with these data |
| Target | Heme oxygenase 1 |
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| Ligand | BDBM651736 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ELISA Assay to Measure Human Heme Oxygenase-1 (HMOX-1) in HepG2 lysate |
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| EC50 | 4000±n/a nM |
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| Citation |  Biddle, M; Kluge, A; Sasmal, S; Lagu, B; Wu, X; Ogiyama, T; Bell, E HMOX1 INDUCERS US Patent US20240051952 Publication Date 2/15/2024 |
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| More Info.: | Get all data from this article, Assay Method |
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| Heme oxygenase 1 |
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| Name: | Heme oxygenase 1 |
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| Synonyms: | HMOX1 | HMOX1_HUMAN | HO | HO-1 | HO1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32822.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_368941 |
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| Residue: | 288 |
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| Sequence: | MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVA
LEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHE
VGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQ
LYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRA
SNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATVAVGLYAM
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| BDBM651736 |
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| n/a |
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| Name | BDBM651736 |
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| Synonyms: | 1-(tetrahydro-2H-pyran- 4-yl)-2-((6-(trifluoro- methoxy)benzo[d]- oxazol-2-yl)amino)- 1H-benzo[d]imidazole- 5-carboxylic acid | US20240051952, Example 79 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H17F3N4O3 |
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| Mol. Mass. | 418.3692 |
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| SMILES | FC(F)(F)Oc1ccc2nc(Nc3nc4ccccc4n3C3CCOCC3)oc2c1 |
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| Structure | 
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