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TargetSigma intracellular receptor 2
LigandBDBM312185
Substrate/Competitorn/a
Meas. Tech.Receptor Assay
Ki 0.560±0.12 nM
Citation McCurdy, CRMesangeau, CChin, FTJames, MLShen, BGambhir, S Highly selective sigma receptor radioligands US Patent US9604926 Publication Date 3/28/2017
More Info.:Get all data from this article,  Assay Method
 
Sigma intracellular receptor 2
Name:Sigma intracellular receptor 2
Synonyms:S2r | SGMR2_MOUSE | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:n/a
Mol. Mass.:20818.69
Organism:Mus musculus (Mouse)
Description:Q8VD00
Residue:176
Sequence:
MGALAARRCVEWLLGLYFVSHIPITLFIDLQAVLPPELYPQEFSNLLRWYSKEFKDPLMQ
EPPVWFKSFLLCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAAHTITTLIPILYTLLF
EDFSKAVAFKGQRPESFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKYEEKRKKK
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  Blast E-value cutoff:
BDBM312185
n/a
NameBDBM312185
Synonyms:US9604926, Compound CM-308 | US9724435, Compound CM-308
TypeSmall organic molecule
Emp. Form.C22H26N2O2S2
Mol. Mass.414.584
SMILESCOc1cc2CCN(CCCCn3c4ccccc4sc3=S)Cc2cc1OC
Structure
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