| Reaction Details |
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 | Report a problem with these data |
| Target | Nucleoprotein |
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| Ligand | BDBM614513 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TBD |
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| EC50 | 20.0±n/a nM |
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| Citation |  BARRETT, M; COCKERILL, GS; GOOD, J; AVERY, CA; COCHRANE, EJ; JONES, SP; ONIONS, ST; WARNER, AJ BENZODIAZEPINE DERIVATIVES USEFUL IN TREATING A RESPIRATORY SYNCYTIAL VIRUS INFECTION US Patent US20230270751 Publication Date 8/31/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Nucleoprotein |
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| Name: | Nucleoprotein |
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| Synonyms: | N | NCAP_HRSVA | Nucleocapsid protein | Protein N |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43455.45 |
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| Organism: | Human respiratory syncytial virus A (strain A2) |
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| Description: | ChEMBL_117398 |
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| Residue: | 391 |
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| Sequence: | MALSKVKLNDTLNKDQLLSSSKYTIQRSTGDSIDTPNYDVQKHINKLCGMLLITEDANHK
FTGLIGMLYAMSRLGREDTIKILRDAGYHVKANGVDVTTHRQDINGKEMKFEVLTLASLT
TEIQINIEIESRKSYKKMLKEMGEVAPEYRHDSPDCGMIILCIAALVITKLAAGDRSGLT
AVIRRANNVLKNEMKRYKGLLPKDIANSFYEVFEKHPHFIDVFVHFGIAQSSTRGGSRVE
GIFAGLFMNAYGAGQVMLRWGVLAKSVKNIMLGHASVQAEMEQVVEVYEYAQKLGGEAGF
YHILNNPKASLLSLTQFPHFSSVVLGNAAGLGIMGEYRGTPRNQDLYDAAKAYAEQLKEN
GVINYSVLDLTAEELEAIKHQLNPKDNDVEL
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| BDBM614513 |
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| n/a |
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| Name | BDBM614513 |
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| Synonyms: | (5R)-2-[2-Fluoro-6-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyridin-3-yl]-5-methyl-N-[(3S)-9-fluoro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-3-yl]-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-carboxamide | US20230270751, Example 90 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H29F2N7O4 |
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| Mol. Mass. | 625.6247 |
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| SMILES | C[C@@H]1CCn2nc(c(C(=O)N[C@H]3N=C(c4ccccc4)c4cccc(F)c4NC3=O)c2O1)-c1ccc(nc1F)N1C[C@H]2C[C@@H]1CO2 |t:12| |
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| Structure | 
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