Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fatty acid-binding protein, adipocyte | ||
| Ligand | BDBM312388 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Time Resolved-Fluorescence Energy Transfer (TR-FRET) Assay | ||
| IC50 | 20.0±n/a nM | ||
| Citation |  Buettelmann, B; Ceccarelli, SM; Kuehne, H; Kuhn, B; Neidhart, W; Obst Sander, U; Richter, H Bicyclic thiophenylamide compounds US Patent US9604977 Publication Date 3/28/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fatty acid-binding protein, adipocyte | |||
| Name: | Fatty acid-binding protein, adipocyte | ||
| Synonyms: | A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | FABP4 | FABP4_HUMAN | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4 | Fatty acid-binding protein 4 (FABP4) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 14719.23 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P15090 | ||
| Residue: | 132 | ||
| Sequence: |
| ||
| BDBM312388 | |||
| n/a | |||
| Name | BDBM312388 | ||
| Synonyms: | 3-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-5,6-dihydro-4H-cyclopenta[b]thiophen-2-ylcarbamoyl]-bicyclo[2.2.2]oct-2-ene-2-carboxylic acid | US9604977, Example 134 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H23N3O4S | ||
| Mol. Mass. | 425.501 | ||
| SMILES | OC(=O)C1=C(C2CCC1CC2)C(=O)Nc1sc2CCCc2c1-c1nc(no1)C1CC1 |t:3,(1.21,-4.41,;2.75,-4.41,;3.52,-5.74,;3.52,-3.07,;2.75,-1.74,;3.52,-.41,;5.06,-.41,;5.83,-1.74,;5.06,-3.07,;3.73,-2.3,;4.86,-1.18,;1.21,-1.74,;.44,-3.07,;.44,-.41,;-1.1,-.41,;-2,-1.65,;-3.47,-1.18,;-4.93,-1.65,;-5.83,-.41,;-4.93,.84,;-3.47,.36,;-2,.84,;-1.23,2.17,;.31,2.17,;.79,3.64,;-.46,4.54,;-1.71,3.64,;2.12,4.41,;3.66,4.41,;2.89,5.74,)| | ||
| Structure | 
| ||