Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fatty acid-binding protein, adipocyte | ||
| Ligand | BDBM312465 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Time Resolved-Fluorescence Energy Transfer (TR-FRET) Assay | ||
| IC50 | 12.0±n/a nM | ||
| Citation |  Buettelmann, B; Ceccarelli, SM; Kuehne, H; Kuhn, B; Neidhart, W; Obst Sander, U; Richter, H Bicyclic thiophenylamide compounds US Patent US9604977 Publication Date 3/28/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fatty acid-binding protein, adipocyte | |||
| Name: | Fatty acid-binding protein, adipocyte | ||
| Synonyms: | A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | FABP4 | FABP4_HUMAN | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4 | Fatty acid-binding protein 4 (FABP4) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 14719.23 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P15090 | ||
| Residue: | 132 | ||
| Sequence: |
| ||
| BDBM312465 | |||
| n/a | |||
| Name | BDBM312465 | ||
| Synonyms: | 3-[3-(3-Cyclopropyl-[1,2,4]thiadiazol-5-yl)-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl]-bicyclo[2.2.2]oct-2-ene-2-carboxylic acid | US9604977, Example 211 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H25N3O3S2 | ||
| Mol. Mass. | 455.593 | ||
| SMILES | OC(=O)C1=C(C2CCC1CC2)C(=O)Nc1sc2CCCCc2c1-c1nc(ns1)C1CC1 |t:3,(1.79,-5.59,;3.28,-5.2,;4.36,-6.28,;3.67,-3.71,;2.9,-2.37,;3.67,-1.04,;5.21,-1.04,;5.98,-2.37,;5.21,-3.71,;3.88,-2.94,;4.97,-1.85,;1.36,-2.37,;.59,-3.71,;.59,-1.04,;-.95,-1.04,;-1.85,-2.29,;-3.32,-1.81,;-4.65,-2.58,;-5.98,-1.81,;-5.98,-.27,;-4.65,.5,;-3.32,-.27,;-1.85,.2,;-1.45,1.69,;.01,2.17,;.01,3.71,;-1.45,4.18,;-2.36,2.94,;1.1,4.8,;2.59,5.2,;1.5,6.28,)| | ||
| Structure | 
| ||