| Reaction Details |
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 | Report a problem with these data |
| Target | Prokineticin receptor 1 |
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| Ligand | BDBM250617 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | BIOLOGICAL ASSAY |
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| IC50 | 4620±n/a nM |
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| Citation |  Carroll, C; Goldby, A; Teall, M Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases US Patent US10167273 Publication Date 1/1/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Prokineticin receptor 1 |
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| Name: | Prokineticin receptor 1 |
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| Synonyms: | G-protein coupled receptor 73 | G-protein coupled receptor ZAQ | GPR73 | GPR73a | PK-R1 | PKR1 | PKR1_HUMAN | PROKR1 |
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| Type: | enzyme |
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| Mol. Mass.: | 44779.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TCW9 |
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| Residue: | 393 |
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| Sequence: | METTMGFMDDNATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFA
AKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEM
DYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTAT
GLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGIE
FVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPF
YGFTIVRDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLH
WKASYNGGKSSADLDLKTIGMPATEEVDCIRLK
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| BDBM250617 |
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| n/a |
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| Name | BDBM250617 |
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| Synonyms: | US10167273, Example 98 | US10544126, Example 96 | US11512066, Example 98 | US9475795, 96 | US9475795, 97 | US9475795, 98 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H24ClN3O3S |
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| Mol. Mass. | 397.919 |
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| SMILES | COC(C1CCN(CC1)S(=O)(=O)c1c(C)n[nH]c1C)c1ccc(Cl)cc1 |
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| Structure | 
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