| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Caspase-7 |
|---|
| Ligand | BDBM160786 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Inhibitory Activity of Caspase |
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| IC50 | 800±n/a nM |
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| Citation |  Ahlfors, J; Mekouar, K Selective caspase inhibitors and uses thereof US Patent US10167313 Publication Date 1/1/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Caspase-7 |
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| Name: | Caspase-7 |
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| Synonyms: | Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase |
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| Type: | Enzyme |
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| Mol. Mass.: | 34273.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55210 |
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| Residue: | 303 |
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| Sequence: | MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
FSQ
|
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|
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| BDBM160786 |
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| n/a |
|---|
| Name | BDBM160786 |
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| Synonyms: | US10167313, Compound 53 | US9045524, 53 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H38N4O11S |
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| Mol. Mass. | 674.719 |
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| SMILES | CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)OCc1ccccc1)c1ccccc1)C(=O)N[C@@H](CC(O)=O)\C=C\S(C)(=O)=O |r| |
|---|
| Structure | 
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