| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Caspase-9 |
|---|
| Ligand | BDBM160781 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In Vitro Inhibitory Activity of Caspase |
|---|
| IC50 | 500±n/a nM |
|---|
| Citation |  Ahlfors, J; Mekouar, K Selective caspase inhibitors and uses thereof US Patent US10167313 Publication Date 1/1/2019 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Caspase-9 |
|---|
| Name: | Caspase-9 |
|---|
| Synonyms: | Apoptotic protease-activating factor 1/Caspase-3/Caspase-9/Cytochrome c | Apoptotic protease-activating factor 3 | CASP-9 | CASP9 | CASP9_HUMAN | Caspase 9 | ICE-like apoptotic protease 6 | MCH6 | caspase-9 isoform alpha preproprotein |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 46277.29 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 416 |
|---|
| Sequence: | MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLII
DLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEV
LRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTR
TGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQ
ASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVAS
TSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSG
SWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS
|
|
|
|---|
| BDBM160781 |
|---|
| n/a |
|---|
| Name | BDBM160781 |
|---|
| Synonyms: | US10167313, Compound 48 | US9045524, 48 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C35H40ClN5O11S |
|---|
| Mol. Mass. | 774.237 |
|---|
| SMILES | CC(C)[C@H](NC(=O)[C@H](Cc1ccc2ccccc2n1)NC(=O)[C@H](CC(O)=O)NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(O)=O)\C=C(/Cl)S(C)(=O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
