| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50077877 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay |
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| Ki | 4.80±n/a nM |
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| Citation |  Torrens-Jover, A; Christmann, U; Diaz-Fernández, J; Almansa-Rosales, C 1,2,3-triazole-4-amine derivatives for the treatment of sigma receptor related diseases and disorders US Patent US9611229 Publication Date 4/4/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Opioid receptor, sigma 1 | Oprs1 | SGMR1_MOUSE | Sigma 1-type opioid receptor | Sigma1-receptor | Sigma1R | Sigmar1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25246.51 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | O55242 |
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| Residue: | 223 |
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| Sequence: | MPWAAGRRWAWITLILTIIAVLIQAAWLWLGTQNFVFSREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCILHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWKEGTTKSEVFYPGETVVHGPGEATALEWGPNTWMVEYGRGVIPS
TLFFALADTFFSTQDYLTLFYTLRAYARGLRLELTTYLFGQDS
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| BDBM50077877 |
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| n/a |
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| Name | BDBM50077877 |
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| Synonyms: | CHEMBL3417042 | US9611229, 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H19Cl2N5 |
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| Mol. Mass. | 340.251 |
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| SMILES | Clc1ccc(cc1Cl)-n1cc(NCCN2CCCCC2)nn1 |
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| Structure | 
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