| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphatidylinositol 3-kinase regulatory subunit beta |
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| Ligand | BDBM315536 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In vitro kinase assay |
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| IC50 | >500±n/a nM |
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| Citation |  Liu, Y; Ren, P; Jessen, K; Guo, X; Rommel, C Combination pharmaceutical compositions and uses thereof US Patent US10172858 Publication Date 1/8/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphatidylinositol 3-kinase regulatory subunit beta |
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| Name: | Phosphatidylinositol 3-kinase regulatory subunit beta |
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| Synonyms: | P85B_HUMAN | PI3-kinase regulatory subunit beta | PI3-kinase subunit p85-beta | PI3K regulatory subunit beta | PIK3R2 | Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta | PtdIns-3-kinase regulatory subunit beta | PtdIns-3-kinase regulatory subunit p85-beta |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 81542.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O00459 |
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| Residue: | 728 |
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| Sequence: | MAGPEGFQYRALYPFRRERPEDLELLPGDVLVVSRAALQALGVAEGGERCPQSVGWMPGL
NERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPRDGAPEPGLTLPDLPEQFSP
PDVAPPLLVKLVEAIERTGLDSESHYRPELPAPRTDWSLSDVDQWDTAALADGIKSFLLA
LPAPLVTPEASAEARRALREAAGPVGPALEPPTLPLHRALTLRFLLQHLGRVASRAPALG
PAVRALGATFGPLLLRAPPPPSSPPPGGAPDGSEPSPDFPALLVEKLLQEHLEEQEVAPP
ALPPKPPKAKPASTVLANGGSPPSLQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSK
IQGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVDLINHYRHESLAQYNAKLDTR
LLYPVSKYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTA
IEAFNETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRT
KLEQQLRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNE
TEDQYALMEDEDDLPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVV
VDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPG
PGPPPAAR
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| BDBM315536 |
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| n/a |
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| Name | BDBM315536 |
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| Synonyms: | US10172858, Table 2.31 | US9828378, # 31 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23N7O2 |
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| Mol. Mass. | 417.4637 |
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| SMILES | Nc1ncnc2n(nc(-c3cc4cc(O)ccc4[nH]3)c12)C1CCN(CC1)C(=O)C1CC1 |
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| Structure | 
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