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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Phosphatidylinositol 3-kinase regulatory subunit beta | ||
| Ligand | BDBM315561 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | In vitro kinase assay | ||
| IC50 | >500±n/a nM | ||
| Citation |  Liu, Y; Ren, P; Jessen, K; Guo, X; Rommel, C Combination pharmaceutical compositions and uses thereof US Patent US10172858 Publication Date 1/8/2019 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Phosphatidylinositol 3-kinase regulatory subunit beta | |||
| Name: | Phosphatidylinositol 3-kinase regulatory subunit beta | ||
| Synonyms: | P85B_HUMAN | PI3-kinase regulatory subunit beta | PI3-kinase subunit p85-beta | PI3K regulatory subunit beta | PIK3R2 | Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta | PtdIns-3-kinase regulatory subunit beta | PtdIns-3-kinase regulatory subunit p85-beta | ||
| Type: | Enzyme Subunit | ||
| Mol. Mass.: | 81542.75 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O00459 | ||
| Residue: | 728 | ||
| Sequence: |
| ||
| BDBM315561 | |||
| n/a | |||
| Name | BDBM315561 | ||
| Synonyms: | US10172858, Table 2.58 | US9828378, # 58 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H30N8O | ||
| Mol. Mass. | 446.548 | ||
| SMILES | CN1CCN(CC1)C1CCC(CC1)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc12 |w:7.7,(.56,-10.64,;.56,-9.1,;-.77,-8.33,;-.77,-6.79,;.56,-6.02,;1.9,-6.79,;1.9,-8.33,;.56,-4.48,;-.77,-3.71,;-.77,-2.17,;.56,-1.4,;1.9,-2.17,;1.9,-3.71,;.56,.14,;1.47,1.39,;.56,2.63,;.96,4.12,;.06,5.37,;.96,6.61,;.64,8.12,;1.79,9.15,;1.39,10.64,;3.25,8.67,;3.57,7.17,;2.43,6.14,;2.43,4.6,;-.9,2.16,;-2.24,2.93,;-2.24,4.47,;-3.57,2.16,;-3.57,.62,;-2.24,-.15,;-.9,.62,)| | ||
| Structure | 
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