| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM317229 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay |
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| Ki | 260±n/a nM |
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| Citation |  Alcalde-Pais, M; Diaz Fernández, JL; Mesquida-Estevez, M; Paloma-Romeu, L Imidazo[2,1-b]thiazole derivatives, their preparation and use as medicaments US Patent US9617281 Publication Date 4/11/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM317229 |
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| n/a |
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| Name | BDBM317229 |
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| Synonyms: | 6-((4- Methylpiperazin-1- ylmethyl)-2- phenylimidazo[2,1- b][1,3,4]thiadiazole maleate | US9617281, Compound 11 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19N5S |
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| Mol. Mass. | 313.421 |
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| SMILES | CN1CCN(Cc2cn3nc(sc3n2)-c2ccccc2)CC1 |
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| Structure | 
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