Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetSigma intracellular receptor 2
LigandBDBM321268
Substrate/Competitorn/a
Meas. Tech.Binding Assay to Sigma Receptors
Ki 20.0±n/a nM
Citation Melnyk, PVermersch, PCarato, POxombre-Vanteghem, BZephir, HDonnier-Marechal, M Compounds, pharmaceutical composition and their use in treating neurodegenerative diseases US Patent US10179761 Publication Date 1/15/2019
More Info.:Get all data from this article,  Assay Method
 
Sigma intracellular receptor 2
Name:Sigma intracellular receptor 2
Synonyms:MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:Protein
Mol. Mass.:20857.20
Organism:Homo sapiens (Human)
Description:Q5BJF2
Residue:176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQ
EPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLF
EDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM321268
n/a
NameBDBM321268
Synonyms:N-[4-(benzylmethylamino)butyl]-4-chlorobenzamide | US10179761, Compound 3.1.11
TypeSmall organic molecule
Emp. Form.C19H23ClN2O
Mol. Mass.330.852
SMILESCN(CCCCNC(=O)c1ccc(Cl)cc1)Cc1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: