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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 4 | ||
| Ligand | BDBM100379 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Omnia Assay | ||
| IC50 | <100±n/a nM | ||
| Citation |  D Agostino, LA; Sjin, RT; Niu, D; McDonald, JJ; Zhu, Z; Liu, H; Mazdiyasni, H; Petter, RC; Singh, J; Barrague, M; Gross, A; Munson, M Heteroaryl compounds and uses thereof US Patent US10189794 Publication Date 1/29/2019 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 4 | |||
| Name: | Fibroblast growth factor receptor 4 | ||
| Synonyms: | CD_antigen: CD334 FGFR4 | FGFR-4 | FGFR4 | FGFR4_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 4 (FGFR4) | JK2 | JTK2 | TKF | ||
| Type: | Protein | ||
| Mol. Mass.: | 87957.45 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22455 | ||
| Residue: | 802 | ||
| Sequence: |
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| BDBM100379 | |||
| n/a | |||
| Name | BDBM100379 | ||
| Synonyms: | US10189794, Compound I-211 | US10618902, Compound I-211 | US10774052, Compound I-211 | US9695132, I-211 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H23Cl2N5O5 | ||
| Mol. Mass. | 520.365 | ||
| SMILES | COc1cc(OC)c(Cl)c(c1Cl)-c1cc2cnc(NC3COCC3NC(=O)C=C)nc2n(C)c1=O |(8.91,2.15,;7.58,1.38,;6.25,2.15,;6.25,3.69,;4.91,4.46,;4.91,6,;6.25,6.77,;3.58,3.69,;2.25,4.46,;3.58,2.15,;4.91,1.38,;4.91,-.16,;2.25,1.38,;.91,2.15,;-.42,1.38,;-1.76,2.15,;-3.09,1.38,;-3.09,-.16,;-4.42,-.93,;-4.42,-2.47,;-3.18,-3.38,;-3.65,-4.84,;-5.19,-4.84,;-5.67,-3.38,;-7.13,-2.9,;-8.28,-3.93,;-7.96,-5.44,;-9.74,-3.46,;-10.89,-4.49,;-1.76,-.93,;-.42,-.16,;.91,-.93,;.91,-2.47,;2.25,-.16,;3.58,-.93,)| | ||
| Structure | 
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