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TargetE2 ubiquitin-conjugating enzyme E1
LigandBDBM329858
Substrate/Competitorn/a
Meas. Tech.HTRF Assay
IC50<10±n/a nM
Citation Afroze RBharathan ITCiavarri JPFleming PEGaulin JLGirard MLangston SPSoucy FWong TYe Y Pyrazolopyrimidinyl inhibitors of ubiquitin-activating enzyme US Patent  US9663525 Publication Date 5/30/2017
More Info.:Get all data from this article,  Assay Method
 
E2 ubiquitin-conjugating enzyme E1
Name:E2 ubiquitin-conjugating enzyme E1
Synonyms:n/a
Type:n/a
Mol. Mass.:21408.98
Organism:Homo sapiens (Human)
Description:P51965
Residue:193
Sequence:
MSDDDSRASTSSSSSSSSNQQTEKETNTPKKKESKVSMSKNSKLLSTSAKRIQKELADIT
LDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIY
HCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEH
DRMARQWTKRYAT
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  Blast E-value cutoff:
BDBM329858
n/a
NameBDBM329858
Synonyms:(rac)-((1R,2R,3S,4R)-2,3-Dihydroxy-4-((2-(2-methoxy-5-(trifluoromethoxy)- | US10202389, Compound I-102 | US9663525, Compound I-066 | US9663525, Compound I-102 | US9796725, Compound I-066
TypeSmall organic molecule
Emp. Form.C20H22F3N5O7S
Mol. Mass.533.478
SMILESCOc1ccc(OC(F)(F)F)cc1-c1cc2nccc(N[C@@H]3C[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]3O)n2n1 |r|
Structure
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