| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier family 22 member 2 |
|---|
| Ligand | BDBM330061 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| IC50 | 450±n/a nM |
|---|
| Citation |  Desai, MC; Jin, H; Lazerwith, SE; Pyun, H; Taylor, JG Substituted 1,2,3,4,6,8,12,12a-octahydro-1,4-methanodipyrido[1,2-a:1',2'-d]pyrazines and methods for treating viral infections US Patent US9663528 Publication Date 5/30/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Solute carrier family 22 member 2 |
|---|
| Name: | Solute carrier family 22 member 2 |
|---|
| Synonyms: | OCT2 | Organic cation transporter 2 | S22A2_HUMAN | SLC22A2 | hOCT2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 62591.01 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1484077 |
|---|
| Residue: | 555 |
|---|
| Sequence: | MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHRCRSPGVAELS
LRCGWSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLG
PCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCL
LTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIF
YQVAYTVGLLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPRWLISQNKNAEAM
RIIKHIAKKNGKSLPASLQRLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFTSSV
LYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLA
SVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLGVHICSSMCDIGGII
TPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENMQRPRKNKE
KMIYLQVQKLDIPLN
|
|
|
|---|
| BDBM330061 |
|---|
| n/a |
|---|
| Name | BDBM330061 |
|---|
| Synonyms: | (1R,4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-6,8-dioxo-1,2,3,4,6,8,12,12a-octahydro-1,4-ethanodipyrido[1,2-a:1′,2′-d]pyrazine-9-carboxamide | US9663528, 100 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H21F2N3O4 |
|---|
| Mol. Mass. | 429.4166 |
|---|
| SMILES | C[C@H]1C[C@@H]2C[C@H]1N1[C@H]2Cn2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O |TLB:0:1:7.6:4,THB:8:7:1.2:4,29:6:1.2:4| |
|---|
| Structure | 
|
|---|
Search and Browse
