| Reaction Details |
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 | Report a problem with these data |
| Target | Eyes absent homolog 3 |
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| Ligand | BDBM50342278 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibitory Assay |
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| IC50 | 17000±n/a nM |
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| Citation |  Hegde, R Use of small molecule inhibitors targeting EYA tyrosine phosphatase US Patent US9725430 Publication Date 8/8/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Eyes absent homolog 3 |
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| Name: | Eyes absent homolog 3 |
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| Synonyms: | EYA3 | EYA3_HUMAN | Eyes absent homolog 3 (EYA3) |
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| Type: | Protein |
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| Mol. Mass.: | 62648.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99504 |
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| Residue: | 573 |
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| Sequence: | MEEEQDLPEQPVKKAKMQESGEQTISQVSNPDVSDQKPETSSLASNLPMSEEIMTCTDYI
PRSSNDYTSQMYSAKPYAHILSVPVSETAYPGQTQYQTLQQTQPYAVYPQATQTYGLPPF
GALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIQASSTNASLISTSST
IANIPAAAVASISNQDYPTYTILGQNQYQACYPSSSFGVTGQTNSDAESTTLAATTYQSE
KPSVMAPAPAAQRLSSGDPSTSPSLSQTTPSKDTDDQSRKNMTSKNRGKRKADATSSQDS
ELERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDL
EECDQVHVEDVASDDNGQDLSNYSFSTDGFSGSGGSGSHGSSVGVQGGVDWMRKLAFRYR
KVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCVNVL
ITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRD
EEIAAKQHNMPFWRITNHGDLVSLHQALELDFL
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| BDBM50342278 |
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| n/a |
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| Name | BDBM50342278 |
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| Synonyms: | (2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone | Benzarone | CHEMBL1474963 | US9725430, Compound 1a | US9962362, Compound 1a |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14O3 |
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| Mol. Mass. | 266.2913 |
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| SMILES | CCc1oc2ccccc2c1C(=O)c1ccc(O)cc1 |
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| Structure | 
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