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TargetSphingosine 1-phosphate receptor 5
LigandBDBM195890
Substrate/Competitorn/a
Meas. Tech.In Vitro Functional Activity (Agonism) on Human 51P5 Receptors
EC50 5.00±n/a nM
Citation Smid, PIwema Bakker, WICoolen, HKSliedregt, LAvan Dongen, MJden Hartog, JAHobson, A Fused heterocyclic derivatives as S1P modulators US Patent US9670220 Publication Date 6/6/2017
More Info.:Get all data from this article,  Assay Method
 
Sphingosine 1-phosphate receptor 5
Name:Sphingosine 1-phosphate receptor 5
Synonyms:EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:41796.42
Organism:Homo sapiens (Human)
Description:n/a
Residue:398
Sequence:
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
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  Blast E-value cutoff:
BDBM195890
n/a
NameBDBM195890
Synonyms:US9670220, 35
TypeSmall organic molecule
Emp. Form.C24H24FNO4
Mol. Mass.409.4501
SMILESOC(=O)CCCN1CCc2oc(cc2C1)-c1ccc(OCc2ccccc2F)cc1
Structure
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