| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 5 |
|---|
| Ligand | BDBM195899 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In Vitro Functional Activity (Agonism) on Human 51P5 Receptors |
|---|
| EC50 | 2.50±n/a nM |
|---|
| Citation |  Smid, P; Iwema Bakker, WI; Coolen, HK; Sliedregt, LA; van Dongen, MJ; den Hartog, JA; Hobson, A Fused heterocyclic derivatives as S1P modulators US Patent US9670220 Publication Date 6/6/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sphingosine 1-phosphate receptor 5 |
|---|
| Name: | Sphingosine 1-phosphate receptor 5 |
|---|
| Synonyms: | EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 41796.42 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 398 |
|---|
| Sequence: | MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
|
|
|
|---|
| BDBM195899 |
|---|
| n/a |
|---|
| Name | BDBM195899 |
|---|
| Synonyms: | US9670220, 85 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H22F4N2O4 |
|---|
| Mol. Mass. | 478.4361 |
|---|
| SMILES | OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(cc2)C(F)(F)F)c(F)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
