| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 2 |
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| Ligand | BDBM335491 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 137±n/a nM |
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| Citation |  Jin, H; Lazerwith, SE; Pyun, H; Bacon, EM; Morganelli, PA; Ji, M Substituted 2,3,4,5,7,9,13,13a-octahydropyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]OXAZEPINES and methods for treating viral infections US Patent US9732092 Publication Date 8/15/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 2 |
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| Name: | Solute carrier family 22 member 2 |
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| Synonyms: | OCT2 | Organic cation transporter 2 | S22A2_HUMAN | SLC22A2 | hOCT2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 62591.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1484077 |
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| Residue: | 555 |
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| Sequence: | MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHRCRSPGVAELS
LRCGWSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLG
PCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCL
LTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIF
YQVAYTVGLLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPRWLISQNKNAEAM
RIIKHIAKKNGKSLPASLQRLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFTSSV
LYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLA
SVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLGVHICSSMCDIGGII
TPFLVYRLTNIWLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENMQRPRKNKE
KMIYLQVQKLDIPLN
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| BDBM335491 |
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| n/a |
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| Name | BDBM335491 |
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| Synonyms: | (13aS)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide | US9732092, Compound 45 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20F3N3O5 |
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| Mol. Mass. | 463.4065 |
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| SMILES | COc1c2C(=O)N3[C@@H]4CC[C@@H](C4)O[C@H]3Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O |r,TLB:4:6:8.9:11| |
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| Structure | 
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