| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM13576 |
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| Substrate/Competitor | BDBM13574 |
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| Meas. Tech. | Serine Protease Inhibition Assay |
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| Ki | 2000±n/a nM |
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| Citation |  Groebke Zbinden, K; Banner, DW; Ackermann, J; D'Arcy, A; Kirchhofer, D; Ji, YH; Tschopp, TB; Wallbaum, S; Weber, L Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors. Bioorg Med Chem Lett15:817-22 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I |
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| Type: | Enzyme |
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| Mol. Mass.: | 25790.52 |
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| Organism: | Bos taurus (bovine) |
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| Description: | P00760 |
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| Residue: | 246 |
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| Sequence: | MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
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| BDBM13576 |
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| BDBM13574 |
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| Name | BDBM13576 |
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| Synonyms: | N-benzyl-2-[(4-carbamimidoylphenyl)amino]-2-(3,4-diethoxyphenyl)acetamide | phenylglycine amide compound 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30N4O3 |
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| Mol. Mass. | 446.5414 |
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| SMILES | CCOc1ccc(cc1OCC)C(Nc1ccc(cc1)C(N)=N)C(=O)NCc1ccccc1 |
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| Structure | 
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