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TargetcAMP-Dependent Protein Kinase (PKA)
LigandBDBM14028
Substrate/CompetitorKemptide
Meas. Tech.Kinase Activity Assay
pH7.6±n/a
Temperature303.15±n/a K
Ki 340±n/a nM
Citation Jacobs MHayakawa KSwenson LBellon SFleming MTaslimi PDoran J The structure of dimeric ROCK I reveals the mechanism for ligand selectivity. J Biol Chem 281:260-8 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Inhibition_Run data,   Solution Info,  Assay Method
 
cAMP-Dependent Protein Kinase (PKA)
Name:cAMP-Dependent Protein Kinase (PKA)
Synonyms:PKA C-alpha | cAMP-dependent protein kinase catalytic subunit alpha | cAMP-dependent protein kinase, alpha-catalytic subunit
Type:Enzyme Catalytic Unit
Mol. Mass.:40579.18
Organism:Mus musculus (mouse)
Description:n/a
Residue:351
Sequence:
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVML
VKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
MEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM14028
Kemptide
Name:Kemptide
Synonyms:Aurora Peptide Substrate
Type:Peptide
Mol. Mass.:773.92
Organism:n/a
Description:50 uM ATP as co-substrate.
Residue:7
Sequence:
LRRASLG