| Reaction Details |
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 | Report a problem with these data |
| Target | Malignant T-cell-amplified sequence 1 |
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| Ligand | BDBM345319 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Assay 4: MCT1-Mediated Lactate Transport in BT20 Breast Cancer Cells |
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| IC50 | 13000±n/a nM |
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| Citation |  Parnell, KM; McCall, J MCT4 inhibitors for treating disease US Patent US10202350 Publication Date 2/12/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Malignant T-cell-amplified sequence 1 |
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| Name: | Malignant T-cell-amplified sequence 1 |
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| Synonyms: | MCT-1 | MCT1 | MCTS1 | MCTS1_HUMAN | Multiple copies T-cell malignancies |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 20563.62 |
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| Organism: | Homo sapiens (human) |
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| Description: | n/a |
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| Residue: | 181 |
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| Sequence: | MFKKFDEKENVSNCIQLKTSVIKGIKNQLIEQFPGIEPWLNQIMPKKDPVKIVRCHEHIE
ILTVNGELLFFRQREGPFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPG
AKLYPAAVDTIVAIMAEGKQHALCVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTY
K
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| BDBM345319 |
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| n/a |
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| Name | BDBM345319 |
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| Synonyms: | US10202350, Example 65 | US10214492, Example 65 | US11292767, Example 65 | US11724989, Example 65 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21ClN2O4S |
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| Mol. Mass. | 420.91 |
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| SMILES | COc1csc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl |
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| Structure | 
|
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